Molecular Diagnostic Unit is now offering BCR-ABL Quantitative service to patients 



Department of Preventive Oncology Research was established in 2013. It is a department focussing on integrated aspects of cancer genomics and precision oncology. The department focus is Oncology based molecular research, molecular diagnostics and molecular prevention based activities.


of the Dept of Preventive Oncology Research is to achieve highest standards in the practice of Oncological Sciences and to strive for promoting patient health and safety.


of the Dept of Preventive Oncology Research is


The department is accredited by NABL for medical testing and offers molecular diagnostics and precision oncology services for hospital patients. The list of services is appended below.

Department is currently involved in developing inhouse diagnostic assays based on quantitative Digital PCR and NGS platforms for the patient fraternity.

Emergency Cases

Please feel welcome to contact our friendly reception staff with any general or medical enquiry call us.

Opening Hours

Monday – Friday :  8.00 am – 7:00 pm
Saturday : 9.00 am – 8.00 pm
Sunday : 10.00 am – 9.00 pm

Registration Time

Monday – Sunday : 7.00 am – 11.00 am

Visiting Hours

Monday – Sunday : 4.00 PM – 6.00 PM

Molecular Prevention

The department of Preventive Oncology Molecular Testing Laboratory is a Centralised Facility for Human papilloma Virus DNA testing as a primary screening modality for cervical cancer screening. The department receives cervical cancer screening samples across the country for the HPV DNA testing. The department has the US-FDA approved fully automated platform, the global standard, Cobas 4800 (Roche Molecular Diagnostics) for the cervical cancer screening. The department is a referral centre for the National Health Mission based cervical cancer screening programs.

Research Activities – Ongoing Projects

Genetic and Proteomic Profiling of Oral Submucous FibrosisICMR, GOVT OF INDIA
Formulation and Characterisation of Nanosilymarin gel and its applications in Oral Submucous FibrosisICMR, GOVT OF INDIA
Study of PAK1 inhibitors in PDX derived Lung CancersDBT, TARE
Study of role Beta Blockers in cancers of gingivobuccal cancersDBT, TARE
Developing AI based models for relapse prediction in pediatric ALLICMR, GOVT OF INDIA
Detecting early cervical cancer in Indian women using a multi-biomarker panel (the CARE study)Public Health Research Institute of India(PHRI, Mysore)
Study of salivary biomarkers in oral cancerPHFI, INDIA
Study of Oral microbiome by 16S RNA sequencingPHFI, INDIA

Clinical Trials Involved:

Phase IIb/III study to determine efficacy of Curcumin (formulation) and Metformin to reduce the incidence of second primary tumors of aerodigestive tract in patients with history of head and neck squamous cell carcinoma. (SPT TRIAL)National Cancer Grid


Student Activities : Internship Programs


Routine Worshops Conducted:


List Of Staff Members :

Dr R Vijayalakshmi, M.Sc., Ph.D.
(Molecular Oncology)

Fellowship in Molecular Prevention (NCI, NIH, USA) Professor and Head,

Miss Soundharya Ravindran B. Tech (Genetic Engg)., MS.
(Cancer Biology, UK)

Scientific Assistant

Mrs A Kanchana M.Sc., DMLT.

Senior Laboratory Technician

Miss Afrose Fathima B.Sc., DMLT.

Laboratory Technician

Dr Sridevi Duggirala M.Sc., Ph.D.

Assistant Professor.

Mr Aravindalochan M.Tech
(Molecular Medicine)

Scientific Assistant

Miss M.Latha, B.Sc., DMLT.

Laboratory Technician

Miss Rachel Gnanamani, MA.

Data Entry Operator

Mrs G Komathi, M.Sc., M.Phil., MBA.
(Hospital Management)


Mr K. Mehanathan M.Sc.


Miss B.Nishanthi B.Sc., DMLT.

Laboratory Technician

List Of Ph.d Scholars (ongoing)

Dr Vani Suresh, MDS.

(Full time)

Dr Vidyarani Shyamsundar MDS.

(Part time)

Dr Divyambika Srinivas MDS.

(Part time)

Other Honours - Dr R Vijayalakshmi

Member Of Professional Bodies

Accomplishments from the Department :

Best Research Paper with Gold Medal at International Conference conducted by Foundation of Head and Neck Oncology (FHNO-2022) for presentation titled “Vimentin as a biomarker for Oral Cancer” (Dr R Vijayalakshmi)

Best Research Paper with Gold Medal at International Conference conducted by Foundation of Head and Neck Oncology (FHNO-2014) for presentation titled “Risk Stratification of Oral Tongue Cancers” (Dr R Vijayalakshmi)

Best Research paper with Cash award – Development of paper based microfluidic based device for detection of HR HPV during screening of cervical cancer (Dr Sridevi Duggirala)

Best Research with Cash award – Cervical cancer screening using HPV DNA testing (Ms Soundarya Ravindran)

Second Prize for Research Paper – Role of SNP in carcinogenesis of gingiva- buccal cancers among long term tobacco chewers (Dr Vidyarani Shyamsundar)

List Of Publications

Cumulative Impact Factor for publications (Dr Vijayalakshmi – 110.149) (Publications – LAST 2 YEARS)

Sharbadeb Kundu 1, Bishal Dhar 2, Raima Das 3, Shaheen Laskar 3, Seram Anil Singh 4, Wetetsho Kapfo 5, Rajesh Paul 6, Vijayalakshmi Ramshankar 7, Yashmin Choudhury 3, Sankar Kumar Ghosh. The impact of prehistoric human dispersals In the presence of tobacco-related oral cancer in Northeast India
Gene. 2022 Mar 1;813:146098. doi: 10.1016/j.gene.2021.146098.
PMID: 34952175 DOI: 10.1016/j.gene.2021.146098 IF – 3.913

Abirami Moorthy 1, Divyambika Catakapatri Venugopal 1, Vidyarani Shyamsundar 2, Yasasve Madhavan 1, Soundharya Ravindran 3, Mehanathan Kuppuloganathan 3, Arvind Krishnamurthy 4, Sathasivasubramanian Sankarapandian 1, Vani Ganapathy 5, Vijayalakshmi Ramshanka Identification of EGFR as a Biomarker in Saliva and Buccal Cells from Oral Submucous Fibrosis Patients-A Baseline Study. Diagnostics (Basel), 2022 Aug 11;12(8):1935. doi: 10.3390/diagnostics12081935. IF – 3.992

Ananthi Sivagnanam 1, Vidyarani Shyamsundar 2, Pallavi Kesavan 1, Arvind Krishnamurthy 3, Soundara Viveka Thangaraj 1, Divyambika Catakapatri Venugopal 4, Hemashree Kasirajan 5, Pratibha Ramani 5, Vinutha Rachapudi Sarma 6, Vijayalakshmi Ramshankar 1 2D-DIGE-Based Proteomic Profiling with Validations Identifies Vimentin as a Secretory Biomarker Useful for Early Detection and Poor Prognosis in Oral Cancers J Oncol, 2022. Apr 22;2022: 4215097. doi: 10.1155/2022/4215097. eCollection 2022. PMID 35498535 IF – 4.375

Divyambika CV, Sathasivasubramanian S, Vidyarai S, RaviDavid A, Harinee S, Vijayalakshmi R. ⦁ Clinicopathological Correlation of Cyclooxygenase 2 Expression in Oral Submucous Fibrosis: An Immunohistochemical Study. J Int Soc Prev Community Dent. 2021 Sep 21;11(5):553-560. eCollection 2021 Sep-Oct. PMID: 34760800 

Vidyarani Shyamsundar  1, Soundara Viveka Thangaraj  2, Arvind Krishnamurthy  3,  Sanjana Vimal 2,  Pallavi  Kesavan  2, Aravinda Babu  1, Masthan Kmk  1,  Vijayalakshmi  Ram shankar  2Exome Sequencing with Validations and Expression of p16/CDKN2A Shows no Association with HPV in Oral Cancers. Asian Pac J Cancer Prev,. 2022 Jan 1;23(1):191-200.  doi: 10.31557/APJCP.2022.23.1.191. PMID 35092388 IF-2.514

Venugopal DC, Ravindran S, Shyamsundar V, Sankarapandian S, Krishnamurthy A, Sivagnanam A, Madhavan Y, Ramshankar V. Integrated Proteomics Based on 2D Gel Electrophoresis and Mass Spectrometry with Validations: Identification of a Biomarker Compendium for Oral Submucous Fibrosis-An Indian Study. J Pers Med 2022 Feb 3;12(2):208.doi: 10.3390/jpm12020208. PMID 35207696 IF-4.945

Thangaraj SV, Shyamsundar V, Krishnamurthy A, Ramshankar V.  Deregulation of extracellular matrix modeling with molecular  prognostic  markers revealed  by  transcriptome sequencing and validations in Oral  Tongue   squamous cell  carcinoma. Sci Rep. 2021, Jan 8;11(1):250. doi: 10.1038/s41598-020-78624- 4. PMID: 33420101 IF-4.38

S  Thambiraj 1,  R Vijayalakshm i 2,  D  Ravi  Shankaran 3 An effective strategy for development of docetaxel encapsulated gold nanoformulations for treatment of prostate cancer. Sci Rep 2021, Feb 2; 11(1) : 2808. doi: 10.1038/s41598-020- 80529-1. PMID: 3353152 IF-4.38

Thambiraj S, Shruthi S, Vijayalakshmi R, Ravishankaran D. Evaluation of cytotoxic activity of docetaxel loaded gold nanoparticles for lung cancer drug delivery. Cancer Treat Res Commun 2019, Doi:10.1016/j.ctarc 2019.100157. PMID 31310876 IF-1.98

Durai L, Vijayalakshmi R, Karunagaran D.A  novel  reporter system for cyclic AMP mediated gene expression in mammalian cells based on synthetic transgene expression system.  Eur J Pharmacol. 2019 Jul 15;855:56-64. Epub 2019 Apr 26. PMID:31034821 IF-4.432

Zargar S, Tomar V, Shyamsundar V, Vijayalakshmi R, Somasundaram K, Karunagaran D. A  Feedback Loop between MicroRNA 155 (miR-155), Programmed Cell  Death  4,  and  Activation  Protein 1  Modulates  the  Expression  of miR-155 and Tumorigenesis in Tongue Cancer.  Mol Cell Biol. 2019 Mar 1;39(6). pii: e00410-18. PMID:30617160 IF-4.272

Kundu S, Ramshankar V, Verma AK, Thangaraj SV, Krishnamurthy A, Kumar R, Kannan R, Ghosh SK ⦁ Association of DFNA5, SYK, and NELL1 variants along with⦁ HPV infection in oral cancer among the prolonged tobacco-chewers. Tumour Biol. 2018 Aug;40(8):1010428318793023. PMID:30091681 IF-3.65

Scientific Meetings Conducted/planned - None Any Innovations:

    Make Appointment

    Call: 044-22209150/22350131 Ext 105/152/164/169/211 between 7AM and 5PM

    Quick Contacts

    Please feel free to contact our friendly staff with any medical enquiry.

    Health Essentials

    News & Articles

    WhatsApp Image 2023-03-15 at 2.03.22 PM

    Dr Rajkumar’s article in the top 100 cancer scientific Reports paper 2022

    Our Hearty Congratulations to our Dr. Rajkumar on behalf of Adyar Cancer Institute! Dr Rajkumar's Article on 'Identification and validation of plasma biomarkers for diagnosis of breast cancer in South…
    Read more
    WhatsApp Image 2023-03-15 at 7.27.13 PM

    Dr. V. Shanta Memorial Oration

    In memory of Dr. Shanta who left a legacy behind, the 2nd Memorial Oration was conducted on the 11 March 2023 graced by the presence of Mr. N Ram, The…
    Read more

    Conditional survival in gastric cancer patients

    This hospital-based study has employed a novel approach for deep understanding of long-term survival among gastric cancer patients treated with a curative intent in the Cancer Institute (W.I.A), Chennai. This…
    Read more